Volume 49/Number 3/Abstract 2
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Acta Parasitologica, Vol.49, No. 3, 2004, 182-189
Ewa Dlugosz(1) and Halina Wedrychowicz(1,2)* - Rodent interleukins - their molecular characteristics and a role in immunological responses against parasitic infections

(1)Department of Parasitology, Faculty of Veterinary Medicine, Warsaw Agriculture University, 8 Ciszewskiego Street, 02-786 Warsaw; (2)Department of Molecular Biology, W. Stefanski Institute of Parasitology, Polish Academy of Sciences, 51/55 Twarda Street, 00-818 Warsaw; Poland
*Corresponding author: halinwe@twarda.pan.pl
ABSTRACT

Interleukins play a very important regulatory role in the immunological system. Much attention is payed to understand their complicated activities during parasite infections. To investigate their presence in host organisms techniques of molecular biology have been applied. Nucleotide sequences of many interleukins have been established and analysed. The coding sequences of different species are highly conserved. Rodents are especially investigated because of their usefulness as laboratory models for many animal and human parasitic diseases. Here we take a look at mouse (Mus musculus), rat (Rattus norvegicus), hamster (Mesocricetus auratus) and guinea pig (Cavia porcellus) interleukins and compare their coding sequences and gene structures.


KEY WORDS: Interleukine gene structures, mouse, rat, hamster, guinea pig, protozoa, helminth

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